Everyone

RamirezMD

Jelly Bean

"Manage any volumetric pump like a TCI device with different intravenous drugs"

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iTIVA is a simulation program that provides information about distribution of drugs based on mathematical models, and it simulate the behavior of a TCI pump (up to 3 drugs at time), obtaining infusion rates to reach and maintain a stable target effect site concentration, those schemes can be implemented in volumetric infusion pumps, and be guided with pharmacokinetics models.
So now pharmacokinetics can become an easy topic and understanding what is going on during a infusion of a intravenous drug, too.

Pharmacokinetic models

iTIVA has 11 drugs y 33 pharmacokinetic models, that are updated continuously:

-Remifentanil
Adults: Minto  
Kids: Rigby-Jones, Ross

-Fentanyl  
Adults: Shafer, Scott  
Kids: Ginsberg, Encinas (Neonates)

-Sufentanil  
Adults: Gepts, Bovill  
Kids: Greely

-Alfentanil  
Adults: Maitre

-Ketamine 
Adults: Domino, Clements-250
  Kids: Herd, Elkomy

-Procaine
Adults: Seifen

-Lidocaine 
Adults: Dyck, Schnider

-Propofol 
Adults: Schnider, Eleveld, Marsh, Cortinez
  Kids: Peadfusor, Kataria, Eleveld

-Dexmedetomidine
  Adults: Dyck, Lin, Venn 
Kids: Potts

-Midazolam 
Adults: Albrecht, Greenblatt

-Tranexamic 
Adults: Grassin-Delyle
Kids: Goobie, Grassun-Delyle

iTIVA also calculate the end tidal (Et) for Isoflurane, Sevoflurane, Desflurane for the MAC age, with the use of the Mapleson equation.

Created by David Ramirez MD, Cali - Colombia. Universidad de Valle. david@itiva.co

• WARNING:

iTIVA is not designed to handle intravenous drugs for individual patients. Its use is limited to educational purposes to demonstrate pharmacokinetic principles when performing intravenous anesthesia. Therefore the user assumes all risks from the use of this application for clinical purposes. 
Infusion schemes are obtained from concentrations based on models published in the medical literature; therefore concentrations achieved from these schemes can vary widely, in the same manner for clinical effects.
This application should only be used by people with extensive knowledge in Anesthesiology.


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